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ORM-10103

ORM-10103 is a potent and selective Na+/Ca2+ exchanger (NCX) inhibitor, exhibiting IC50 values in the nanomolar range. It effectively suppresses early and delayed afterdepolarizations in cardiac tissue, making it a valuable research tool for studying arrhythmia mechanisms and calcium dysregulation in both cellular and isolated heart experiments.

Product Specifications

CAS Number

488847-28-5

Product Name Alternative

NCX, ORM 10103, ORM10103, ORM-10103, CalciumChannel, Calcium Channel

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Purity

99.15% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.74 mM) ; DMSO:45 mg/mL (129.18 mM)

Smiles

[O-][N+] (=O) c1ccc (Oc2ccc3OC (CCc3c2) c2ccccc2) nc1

Molecular Formula

C20H16N2O4

Molecular Weight

348.35

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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