ORM-10103
ORM-10103 is a potent and selective Na+/Ca2+ exchanger (NCX) inhibitor, exhibiting IC50 values in the nanomolar range. It effectively suppresses early and delayed afterdepolarizations in cardiac tissue, making it a valuable research tool for studying arrhythmia mechanisms and calcium dysregulation in both cellular and isolated heart experiments.
Product Specifications
CAS Number
488847-28-5
Product Name Alternative
NCX, ORM 10103, ORM10103, ORM-10103, CalciumChannel, Calcium Channel
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
99.15% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.74 mM) ; DMSO:45 mg/mL (129.18 mM)
Smiles
[O-][N+] (=O) c1ccc (Oc2ccc3OC (CCc3c2) c2ccccc2) nc1
Molecular Formula
C20H16N2O4
Molecular Weight
348.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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