OSMI-4
OSMI-4 is a potent and cell-permeable O-GlcNAc transferase (OGT) inhibitor, exhibiting low nanomolar biochemical activity and a cellular EC50 of 3 μM. This small molecule is a valuable chemical probe for investigating O-GlcNAcylation in various human cell lines, supporting research in cellular signaling, metabolism, and related disease models.
Product Specifications
CAS Number
2260791-14-6
Product Name Alternative
OSMI 4, OSMI4, OSMI-4, O-GlcNAc transferase (OGT)
Field of Research
Metabolism Research
Purity
99.28% (May vary between batches)
Solubility
DMSO:252.5 mg/mL (417.98 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (8.28 mM)
Smiles
CCOC (=O) CN (Cc1cccs1) C (=O) [C@H] (NS (=O) (=O) c1cc2ccc (=O) [nH]c2cc1Cl) c1ccccc1OC
Molecular Formula
C27H26ClN3O7S2
Molecular Weight
604.09
Storage Conditions
-20°C
Notes
For research use only.
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