OT-82
OT-82 is a potent, selective, and orally bioavailable NAMPT inhibitor with anticancer activity. It demonstrates cytotoxicity, impairs tumor growth in EWS xenograft models, and prolongs survival in mice. This compound is used in research applications for studying leukemias and other cancers in both in vitro and in vivo experimental settings.
Product Specifications
CAS Number
1800487-55-1
Product Name Alternative
NAMPT, Nampt, OT82, OT-82, OT 82
Field of Research
Cell Biology, Metabolism Research, Protein Biochemistry
Purity
98.91% (May vary between batches)
Solubility
DMSO:80 mg/mL (188.47 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.77 mM)
Smiles
O=C (NCCCC=1C=NNC1) C=2C=CC (=C (C#CC3=CC=C (F) C=C3) C2) C=4C=CN=CC4
Molecular Formula
C26H21FN4O
Molecular Weight
424.47
Storage Conditions
-20°C
Notes
For research use only.
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