PAT-1251 Hydrochloride
PAT-1251 Hydrochloride is a potent, selective, and orally bioavailable small molecule inhibitor targeting lysyl oxidase-like 2 (LOXL2), with IC50 values of 0.71 μM for hLOXL2 and 1.17 μM for hLOXL3. It is a valuable research tool for investigating the role of LOXL2 in fibrotic diseases, cancer metastasis, and cardiovascular remodeling in both cellular and animal models.
Product Specifications
CAS Number
2098884-53-6
Field of Research
Neuroscience
Smiles
O (C=1N=C (C (F) (F) F) C=C (CN) C1) C2=CC (C (=O) N3C[C@@H] (F) [C@H] (O) C3) =CC=C2.Cl
Molecular Formula
C18H18ClF4N3O3
Molecular Weight
435.8
Storage Conditions
-20°C
Notes
For research use only.
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