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Paxilline

Paxilline is a fungal indole alkaloid that potently and selectively inhibits BK potassium channels and SERCA. It is widely used as a pharmacological tool in neuroscience research, with studies demonstrating its ability to mitigate synaptic and cognitive deficits in murine models of thalidomide-induced dysfunction.

Product Specifications

CAS Number

57186-25-1

Field of Research

Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery

Smiles

[H][C@]12Cc3c ([nH]c4ccccc34) [C@]1 (C) [C@@]1 (C) CC[C@]3 ([H]) O[C@@] ([H]) (C (=O) C=C3[C@]1 (O) CC2) C (C) (C) O

Molecular Formula

C27H33NO4

Molecular Weight

435.56

Storage Conditions

-20°C

Notes

For research use only.

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