PD 90780
PD 90780 is a small molecule, non-peptide antagonist of nerve growth factor (NGF) that specifically disrupts the interaction between NGF and its p75NTR receptor. It demonstrates inhibitory activity with IC50 values of 23.1 μM and 1.8 μM in PC12 and PC12nnr5 cell-based assays, respectively. This compound is a valuable research tool for studying NGF signaling pathways in neurobiology, pain research, and cellular differentiation models.
Product Specifications
CAS Number
77422-99-2
Product Name Alternative
PD 90780, PD90780, PD-90780
Field of Research
Signal Transduction
Purity
98.75% (May vary between batches)
Solubility
DMSO:28.8 mg/mL (79.48 mM)
Smiles
Cn1c2cc (nn2c (=O) c2cc (NC (=O) c3ccccc3) ccc12) C (O) =O
Molecular Formula
C19H14N4O4
Molecular Weight
362.34
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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