PF-04957325
PF-04957325 is a potent, selective PDE8 inhibitor with IC50 values of 0.7 nM for PDE8A and 0.3 nM for PDE8B. It serves as a valuable research tool for investigating PDE8 biology in models of autoimmune diseases like encephalomyelitis, applicable in both in vitro and in vivo studies.
Product Specifications
CAS Number
1305115-80-3
Product Name Alternative
PF 04957325, PF04957325, PF-04957325, PDE8
Field of Research
Metabolism Research
Purity
99.02% (May vary between batches)
Solubility
DMSO:80 mg/mL (199.81 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8.24 mM)
Smiles
Nc1nc (nc2n (C[C@H]3CN (Cc4nccs4) CCO3) nnc12) C (F) (F) F
Molecular Formula
C14H15F3N8OS
Molecular Weight
400.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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