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PF-2771

PF-2771 is a potent and selective CENP-E inhibitor with an IC50 of 16.1 nM, disrupting mitotic kinesin motor function. This investigational agent has demonstrated antitumor activity in preclinical cancer models, supporting its use in cellular and in vivo research on mitosis and oncology.

Product Specifications

CAS Number

2070009-55-9

Field of Research

Signal Transduction

Smiles

CC (C) Oc1ccc (cc1Cl) C (=O) N[C@H] (CNC (=O) CN (C) C) Cc1ccc (cc1) -c1cn (C) c (n1) C (C) =O

Molecular Formula

C29H36ClN5O4

Molecular Weight

554.08

Storage Conditions

-20°C

Notes

For research use only.

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