PF-543 Citrate
PF-543 Citrate is a potent and selective sphingosine kinase 1 (SPHK1) inhibitor that blocks S1P formation. It exhibits anticancer, antifibrotic, and anti-inflammatory properties, making it a valuable research tool for studying diseases like colorectal cancer in both cellular and animal models.
Product Specifications
CAS Number
1415562-83-2
Product Name Alternative
S1PReceptor, S1P Receptor, SPHK1, Sphingosine Kinase 1 Inhibitor II Citrate, Sphingosine 1-phosphate, PF 543 Citrate, PF543 Citrate, PF-543 Citrate
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
99.33% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.02 mM) ; H2O:40 mg/mL (60.82 mM) ; DMSO:80 mg/mL (121.63 mM)
Smiles
C (CC (O) =O) (CC (O) =O) (C (O) =O) O.C (N1[C@@H] (CO) CCC1) C2=CC=C (COC3=CC (CS (=O) (=O) C4=CC=CC=C4) =CC (C) =C3) C=C2
Molecular Formula
C33H39NO11S
Molecular Weight
657.73
Storage Conditions
-20°C
Notes
For research use only.
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