Digeranyl bisphosphonate
Digeranyl bisphosphonate (DGBP) is a cell-permeable inhibitor of geranylgeranyl pyrophosphate synthase (GGPPS), blocking the geranylgeranylation of proteins such as Rac1. This compound induces autophagy and is a useful tool for studying protein prenylation, autophagy pathways, and related diseases in cellular models.
Product Specifications
CAS Number
878143-03-4
Product Name Alternative
Digeranyl bisphosphonate, DGBP, Rac1, Ras
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
96.07% (May vary between batches)
Solubility
H2O:1.67 mg/mL (3.11 mM) ; Ethanol:< 0.5 mg/mL (Insoluble) ; DMSO:< 0.5 mg/mL (Insoluble)
Smiles
C/C (C) =C\CC/C (C) =C/CC (P ([O-]) ([O-]) =O) (P ([O-]) ([O-]) =O) C/C=C (C) /CC/C=C (C) \C.[Na+].[Na+].[Na+].[Na+]
Molecular Formula
C21H34Na4O6P2
Molecular Weight
536.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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