PIM1-IN-1
PIM1-IN-1 is a highly selective small molecule inhibitor of PIM kinases, demonstrating potent activity against PIM1 (IC50 = 7 nM) and PIM3, with significantly less effect on PIM2. It exhibits antiproliferative effects in vitro and has shown efficacy in reducing tumor growth in xenograft models, supporting its use in cancer research.
Product Specifications
CAS Number
1417630-95-5
Field of Research
Epigenetics & Chromatin, Signal Transduction
Purity
98.59% (May vary between batches)
Smiles
N=1N=C2C=3OCCN (C3C=NN2C1C4=NC=5C (=CC=CC5NCC6CCNCC6) C=C4) CCOC
Molecular Formula
C25H30N8O2
Molecular Weight
474.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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