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PKC-theta inhibitor 1

PKC-theta inhibitor 1 is a potent and selective small molecule antagonist of protein kinase C theta (PKCθ), exhibiting a Ki of 6 nM. This compound is a valuable research tool for investigating T-cell activation and signaling pathways in immunological and inflammatory disease models, both in cellular assays and in vivo studies.

Product Specifications

CAS Number

1160501-81-4

Field of Research

Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction

Smiles

C (F) (F) (F) C=1C2=C (C=CN=C2NN1) C3=CC (=CC=C3) C4 (CN) COC4

Molecular Formula

C17H15F3N4O

Molecular Weight

348.32

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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