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PQCA

PQCA is a highly selective positive allosteric modulator of the muscarinic M1 receptor, exhibiting EC50 values of 49 nM (rhesus) and 135 nM (human) . It shows promise in preclinical research for addressing cognitive deficits, such as those in Alzheimer's disease models, and is inactive at other muscarinic receptor subtypes.

Product Specifications

CAS Number

1144504-35-7

Product Name Alternative

MAChR, PQCA

Field of Research

Neuroscience

Purity

98.95% (May vary between batches)

Solubility

DMSO:< 1 mg/mL (insoluble or slightly soluble)

Smiles

OC (=O) c1cc (CN2CCC (CC2) (C#N) c2ccccn2) c2ccccn2c1=O

Molecular Formula

C22H20N4O3

Molecular Weight

388.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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