PQCA
PQCA is a highly selective positive allosteric modulator of the muscarinic M1 receptor, exhibiting EC50 values of 49 nM (rhesus) and 135 nM (human) . It shows promise in preclinical research for addressing cognitive deficits, such as those in Alzheimer's disease models, and is inactive at other muscarinic receptor subtypes.
Product Specifications
CAS Number
1144504-35-7
Product Name Alternative
MAChR, PQCA
Field of Research
Neuroscience
Purity
98.95% (May vary between batches)
Solubility
DMSO:< 1 mg/mL (insoluble or slightly soluble)
Smiles
OC (=O) c1cc (CN2CCC (CC2) (C#N) c2ccccn2) c2ccccn2c1=O
Molecular Formula
C22H20N4O3
Molecular Weight
388.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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