PRMT5-IN-1
PRMT5-IN-1 is a potent, covalent inhibitor of protein arginine methyltransferase 5 (PRMT5), demonstrating an IC50 of 11 nM against the PRMT5/MEP50 complex. This compound is a valuable chemical probe for investigating PRMT5 function in oncology and hematology research, supporting both in vitro biochemical and cellular studies.
Product Specifications
CAS Number
2366149-83-7
Field of Research
Epigenetics & Chromatin
Smiles
O[C@H]1[C@H] (N2C3=C (C=4N (C=N3) C (O) CN4) C=C2) O[C@] ([C@H] (O) C5=CC=C (Cl) C=C5) ([C@H]1O) [H]
Molecular Formula
C19H19ClN4O5
Molecular Weight
418.83
Storage Conditions
-20°C
Notes
For research use only.
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