(R) -CR8 trihydrochloride
CR8, the (R) -enantiomer trihydrochloride salt, is a molecular glue degrader and potent inhibitor of CDK1/2/5/7/9. It exhibits neuroprotective properties and induces apoptotic cell death, making it a valuable research tool for studying cell cycle dynamics, neurobiology, and cancer mechanisms in both in vitro and in vivo models.
Product Specifications
CAS Number
1786438-30-9
Product Name Alternative
CR 8, CR 8 Trihydrochloride, CR8, CR-8, CR8 Trihydrochloride, CR-8 Trihydrochloride, CR8, (R) -Isomer trihydrochloride, CR8, Isomer, CR8, Isomer Trihydrochloride, CDK2, cdk2/cyclin A, CDK1, CDK1/cyclinB1, CDK9/Cyclin T, CDK5, CDK2/cyclinE, Cdk5/p25, CDK7, CDK7/cyclin H, CDK9, CK1δ/ε, (R) CR8 trihydrochloride, (R) -CR-8 trihydrochloride, (R) -CR8 trihydrochloride, (R) CR8 trihydrochloride, Apoptosis
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
99.33% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.7 mM) ; DMSO:30 mg/mL (55.46 mM)
Smiles
Cl.Cl.Cl.CC[C@H] (CO) Nc1nc (NCc2ccc (cc2) -c2ccccn2) c2ncn (C (C) C) c2n1
Molecular Formula
C24H32Cl3N7O
Molecular Weight
540.92
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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