(Rac) -Acolbifene
(Rac) -Acolbifene (EM-343) is the racemic mixture of the selective estrogen receptor modulator (SERM) Acolbifene. This compound, which features a piperidine ring, acts as an estrogen receptor antagonist with a relative binding affinity (RBA) of 380, demonstrating both anti-estrogenic and estrogenic activities in research models. It is utilized in preclinical studies to investigate hormone-responsive conditions such as breast cancer.
Product Specifications
CAS Number
151533-34-5
Product Name Alternative
Acolbifene, (Rac) -EM-652, EstrogenReceptor, estrogen receptor, Estrogen Receptor, EM343, EM-343, EM 652, EM652, EM-652, EM 343, ERR
Field of Research
Metabolism Research, Signal Transduction
Purity
98.18% (May vary between batches)
Solubility
DMSO:90 mg/mL (196.7 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.21 mM)
Smiles
CC1=C (C (Oc2cc (O) ccc12) c1ccc (OCCN2CCCCC2) cc1) c1ccc (O) cc1
Molecular Formula
C29H31NO4
Molecular Weight
457.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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