(Rac) -AMG8379
AMG8379 is a selective, orally bioavailable sulfonamide antagonist of the voltage-gated sodium channel NaV1.7. Its racemic mixture, (Rac) -AMG8379, is used in research to investigate NaV1.7's role in pain signaling through in vitro electrophysiology and in vivo preclinical models.
Product Specifications
CAS Number
1641574-26-6
Product Name Alternative
Sodium Channel, SodiumChannel, AMG8380, AMG-8380, AMG 8379, AMG 8380, AMG8379, AMG-8379, (Rac) -AMG8380, Nav1.7 channel
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
99.60% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:2.5 mg/mL (4.6 mM) ; DMSO:50 mg/mL (91.92 mM)
Smiles
O=C1N (C=2C (=CC (S (NC=3C=CON3) (=O) =O) =CC2) C=C1) C4=C (OC) C=C (C (F) =C4) C5=CC (Cl) =CC (F) =C5
Molecular Formula
C25H16ClF2N3O5S
Molecular Weight
543.93
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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