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PF-06250112

PF-06250112 is a potent and selective small molecule inhibitor of Bruton's tyrosine kinase (BTK) with an IC50 of 0.5 nM. It also potently inhibits the related kinases BMX and TEC. This inhibitor is a valuable research tool for studying B-cell signaling pathways in both in vitro and in vivo models of autoimmune diseases and B-cell malignancies.

Product Specifications

CAS Number

1609465-89-5

Field of Research

Cardiovascular Research, Signal Transduction

Smiles

C (N) (=O) C=1C (=NN (C1N) [C@@H]2CN (C#N) CCC2) C3=CC=C (OC4=C (F) C=C (F) C=C4) C=C3

Molecular Formula

C22H20F2N6O2

Molecular Weight

438.43

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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