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Retaspimycin

Retaspimycin is a water-soluble, potent inhibitor of Hsp90 and Grp94, exhibiting EC50 values of 119 nM for each target. This compound is utilized in cancer research to study oncoprotein degradation and has demonstrated antitumor efficacy in both cellular assays and in vivo xenograft models.

Product Specifications

CAS Number

857402-23-4

Field of Research

Metabolism Research, Signal Transduction

Smiles

N (CC=C) C1=C2C (O) =C (C=C1O) NC (=O) \C (\C) =C/C=C/[C@H] (OC) [C@@H] (OC (N) =O) \C (\C) =C\[C@H] (C) [C@@H] (O) [C@@H] (OC) C[C@H] (C) C2

Molecular Formula

C31H45N3O8

Molecular Weight

587.7

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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