RIPK1-IN-4
RIPK1-IN-4 is a potent and selective type II inhibitor that targets the inactive DLG-out conformation of RIP1 kinase, exhibiting IC50 values of 16 nM and 10 nM in respective assays. This compound is a valuable research tool for investigating necroptosis and inflammatory pathways in both cellular and animal models of disease.
Product Specifications
CAS Number
1481641-08-0
Product Name Alternative
ADP-Glo, RIPkinase, RIPK1 IN 4, RIPK1IN4, RIPK-1-IN-4, RIPK1-IN-4, RIP1, RIP kinase
Field of Research
Cell Biology, Signal Transduction
Purity
99.66% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (12.45 mM) ; DMSO:225 mg/mL (560.45 mM)
Smiles
CC (C) (C) c1cc (NC (=O) Nc2ccc (cc2) -c2cccc3c (N) nccc23) no1
Molecular Formula
C23H23N5O2
Molecular Weight
401.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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