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RORγt Inverse agonist 3

RORγt Inverse agonist 3 is a potent, selective, and orally bioavailable inverse agonist for the RORγ and RORγt receptors, with EC50 values of 0.22 μM and 0.15 μM, respectively. This small molecule is a valuable research tool for investigating Th17 cell biology and autoimmune diseases in both cellular and animal models.

Product Specifications

CAS Number

2364429-77-4

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Smiles

CNC (=O) [C@@H]1CCCN1S (=O) (=O) c1ccc (Cl) c (COc2cccc3c (cc (nc23) C (C) C) -c2cncn2C) c1Cl

Molecular Formula

C29H31Cl2N5O4S

Molecular Weight

616.56

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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