RORγt Inverse agonist 3
RORγt Inverse agonist 3 is a potent, selective, and orally bioavailable inverse agonist for the RORγ and RORγt receptors, with EC50 values of 0.22 μM and 0.15 μM, respectively. This small molecule is a valuable research tool for investigating Th17 cell biology and autoimmune diseases in both cellular and animal models.
Product Specifications
CAS Number
2364429-77-4
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
CNC (=O) [C@@H]1CCCN1S (=O) (=O) c1ccc (Cl) c (COc2cccc3c (cc (nc23) C (C) C) -c2cncn2C) c1Cl
Molecular Formula
C29H31Cl2N5O4S
Molecular Weight
616.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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