RR-11a analog
RR-11a analog (7a) is a potent aza-peptide Michael acceptor inhibitor of asparaginyl endopeptidase (AE) . It demonstrates nanomolar IC50 values against AEs from Trichomonas vaginalis (4.5 nM), Ixodes ricinus (4.5 nM), and Schistosoma mansoni (31 nM) . This compound is a valuable research tool for studying cysteine protease function in parasitology and for inhibitor development in vitro.
Product Specifications
CAS Number
685543-66-2
Product Name Alternative
Parasite, aza-peptide Michael acceptor, 7a, AE1 in Trichomonas Vaginalis, AE in Ixodes ricinus, AE in Schistosoma mansoni, RR-11a analog
Field of Research
Infectious Disease & Virology, Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology
Purity
98.64% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.14 mM) ; DMSO:112.5 mg/mL (228.9 mM)
Smiles
CCOC (=O) \C=C\C (=O) N (CC (N) =O) NC (=O) [C@H] (C) NC (=O) [C@H] (C) NC (=O) OCc1ccccc1
Molecular Formula
C22H29N5O8
Molecular Weight
491.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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