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RTC-5

RTC-5 (TRC-382) is a phenothiazine-derived small molecule with potent anti-cancer activity. It demonstrates efficacy in EGFR-driven xenograft models by concurrently inhibiting the PI3K/AKT and RAS/ERK signaling pathways, making it a useful research tool for studying oncogenic signaling and tumor growth in vitro and in vivo.

Product Specifications

CAS Number

1423077-49-9

Product Name Alternative

EGFR, RTC 5, RTC5, RTC-5, TRC 382, TRC382, TRC-382

Field of Research

Cardiovascular Research, Signal Transduction

Purity

98.14% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.96 mM) ; DMSO:50 mg/mL (97.86 mM)

Smiles

FC (F) (F) Oc1ccc (cc1) S (=O) (=O) NCCCN1c2ccccc2CCc2ccc (Cl) cc12

Molecular Formula

C24H22ClF3N2O3S

Molecular Weight

510.96

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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