RU-SKI 43
RU-SKI 43 is a selective hedgehog acyltransferase (Hhat) inhibitor (IC50 = 850 nM) with anticancer properties. It suppresses lung adenocarcinoma cell growth in vitro by inhibiting non-canonical Gli-1 activation and downregulating Akt/mTOR signaling pathways.
Product Specifications
CAS Number
1043797-53-0
Product Name Alternative
Hhat, Hedgehog, Acyltransferase, RUSKI 43, RU-SKI 43, RUSKI43, RUSKI-43, Smoothened
Field of Research
Metabolism Research, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology
Purity
99.78% (May vary between batches)
Smiles
C (OC1=CC (C) =CC=C1) C2C3=C (CCN2C (CNCC (CC) C) =O) SC=C3
Molecular Formula
C22H30N2O2S
Molecular Weight
386.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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