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S55746 hydrochloride

S55746 hydrochloride is a potent, orally bioavailable, and selective BCL-2 inhibitor with low nanomolar affinity (Ki=1.3 nM) . It demonstrates antitumor efficacy in preclinical in vivo models with a favorable toxicity profile, making it a valuable tool for oncology research targeting apoptosis pathways.

Product Specifications

CAS Number

1448525-91-4

Field of Research

Cell Biology

Smiles

Cl.Oc1ccc (cc1) N (C (=O) c1cc (-c2cc3OCOc3cc2C (=O) N2Cc3ccccc3C[C@H]2CN2CCOCC2) n2CCCCc12) c1ccccc1

Molecular Formula

C43H43ClN4O6

Molecular Weight

747.28

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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