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SB-657510

SB-657510 is a potent urotensin-II receptor (UT) antagonist with species-variable binding affinity, exhibiting anti-inflammatory effects by blocking UII-induced mediators in vascular endothelial cells. It has demonstrated therapeutic potential in preclinical models of diabetes-associated atherosclerosis.

Product Specifications

CAS Number

474960-44-6

Product Name Alternative

SB 657510, SB657510, SB-657510, urotensin-II (UT), Neurotensin Receptor, NeurotensinReceptor

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Purity

98.03% (May vary between batches)

Solubility

DMSO:27 mg/mL (53.38 mM)

Smiles

COc1cc (Br) c (cc1OC) S (=O) (=O) Nc1ccc (Cl) c (O[C@@H]2CCN (C) C2) c1

Molecular Formula

C19H22BrClN2O5S

Molecular Weight

505.81

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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