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SGC-iMLLT

SGC-iMLLT is a first-in-class, potent chemical probe that selectively inhibits MLLT1 and MLLT3 interactions with histones. It demonstrates cellular target engagement and is a valuable tool for studying the role of these YEATS domain proteins in transcriptional regulation, chromatin remodeling, and associated diseases in biochemical and cellular assays.

Product Specifications

CAS Number

2255338-25-9

Product Name Alternative

MLLT1, MLLT1 YD, MLLT3, MLLT3 YD, Inhibitor, inhibit, HistoneMethyltransferase, Histone Methyltransferase, Epigenetic Reader Domain, SGCiMLLT, SGC-iMLLT, SGC iMLLT

Field of Research

Epigenetics & Chromatin

Purity

>98%

Form

Powder

Solubility

Soluble in DMSO (up to 50 mg/ml)

Smiles

C[C@H]1CCCN1Cc1nc2cc (NC (=O) c3ccc4n (C) ncc4c3) ccc2[nH]1

Molecular Formula

C22H24N6O

Molecular Weight

388.5

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

(S) -1-Methyl-N- (2- ((2-methylpyrrolidin-1-yl) methyl) -1H-benzo[d]imidazole-5-yl) -1H-indazole-5-carboxamide

Available Sizes

Frequently Asked Questions

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