SGC-iMLLT
SGC-iMLLT is a first-in-class, potent chemical probe that selectively inhibits MLLT1 and MLLT3 interactions with histones. It demonstrates cellular target engagement and is a valuable tool for studying the role of these YEATS domain proteins in transcriptional regulation, chromatin remodeling, and associated diseases in biochemical and cellular assays.
Product Specifications
CAS Number
2255338-25-9
Product Name Alternative
MLLT1, MLLT1 YD, MLLT3, MLLT3 YD, Inhibitor, inhibit, HistoneMethyltransferase, Histone Methyltransferase, Epigenetic Reader Domain, SGCiMLLT, SGC-iMLLT, SGC iMLLT
Field of Research
Epigenetics & Chromatin
Purity
>98%
Form
Powder
Solubility
Soluble in DMSO (up to 50 mg/ml)
Smiles
C[C@H]1CCCN1Cc1nc2cc (NC (=O) c3ccc4n (C) ncc4c3) ccc2[nH]1
Molecular Formula
C22H24N6O
Molecular Weight
388.5
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
(S) -1-Methyl-N- (2- ((2-methylpyrrolidin-1-yl) methyl) -1H-benzo[d]imidazole-5-yl) -1H-indazole-5-carboxamide
Available Sizes
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