SGK1-IN-1
SGK1-IN-1 (compound 14n) is a potent and selective inhibitor of Serum/Glucocorticoid Regulated Kinase 1, demonstrating IC50 values of 41 nM, 128 nM, and 310 nM against hSGK1, 2, and 3, respectively, at physiological ATP levels. This tool compound enables the investigation of SGK1 signaling in cancer biology and metabolic disorder research, supporting both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1279829-87-6
Product Name Alternative
SGK-1, SGK1IN1, SGK1-IN-1, SGK-1-IN-1, SGK1 IN 1
Field of Research
Cell Biology, Metabolism Research
Solubility
10% DMSO+90% Saline:2 mg/mL (4.78 mM) ; H2O:1.5 mg/mL (3.58 mM) ; DMSO:40 mg/mL (95.5 mM)
Smiles
O=S (=O) (NC=1C=CC (=CC1) C2=NC=3NN=C (N) C3N=C2) C4=CC (Cl) =CC=C4F
Molecular Formula
C17H12ClFN6O2S
Molecular Weight
418.83
Storage Conditions
-20°C
Notes
For research use only.
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