Silvestrol aglycone
Silvestrol aglycone is a synthetic analog of the natural compound Silvestrol. It potently inhibits cap-dependent translation initiation, demonstrating anti-cancer activity in vitro with EC50 values of 10 nM and 200 nM in myc-LUC and tub-LUC reporter assays, respectively. This mechanism supports its investigation in oncology research for targeting protein synthesis in malignant cells.
Product Specifications
CAS Number
960365-65-5
Smiles
COC (=O) [C@H]1[C@@H] (O) [C@@]2 (O) c3c (O[C@]2 ([C@@H]1c1ccccc1) c1ccc (OC) cc1) cc (O) cc3OC
Molecular Formula
C27H26O8
Molecular Weight
478.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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