SIRT5 inhibitor 1
SIRT5 inhibitor 1 is a potent and selective small molecule targeting human SIRT5 deacylase with an IC50 of 0.11 μM. It serves as a valuable chemical probe for investigating SIRT5's role in metabolic regulation, cancer, and ageing-related pathologies in both cellular and animal models.
Product Specifications
CAS Number
2166487-21-2
Product Name Alternative
Sirtuin, SIRT5 inhibitor 1, SIRT-5 inhibitor 1
Field of Research
Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery
Purity
97.80% (May vary between batches)
Solubility
DMSO:50 mg/mL (74.09 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.96 mM)
Smiles
OC (=O) CCNC (=S) NCCCC[C@H] (NS (=O) (=O) c1cccc (F) c1) C (=O) N[C@@H] (Cc1c[nH]c2ccccc12) C (=O) NC1CCC1
Molecular Formula
C31H39FN6O6S2
Molecular Weight
674.81
Storage Conditions
-20°C
Notes
For research use only.
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