SK1-IN-1
SK1-IN-1 is a potent and orally bioavailable SPHK1 inhibitor (IC50 = 58 nM) . It is used in cancer and neurodegenerative disease research, with studies demonstrating its utility in both in vitro cell-based assays and in vivo animal models.
Product Specifications
CAS Number
1218816-71-7
Product Name Alternative
S1P Receptor, S1PReceptor, SPHK1, SK1IN1, SK-1-IN-1, SK1-IN-1, SK1 IN 1
Field of Research
Pharmacology & Drug Discovery
Purity
98.72% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8.28 mM) ; DMSO:80 mg/mL (200.75 mM)
Smiles
C (CC1CCCC1) C2=NC (=NO2) C3=CC=C ([C@@H] (NC (=O) [C@@H]4[C@@H] (O) CCN4) C) C=C3
Molecular Formula
C22H30N4O3
Molecular Weight
398.5
Storage Conditions
-20°C
Notes
For research use only.
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