SM-164 Hydrochloride (957135-43-2 free base)
SM-164 Hydrochloride is a potent, cell-permeable Smac mimetic that antagonizes XIAP by binding with high affinity (IC50 = 1.39 nM) to its BIR2 and BIR3 domains. It is widely used in cancer research to study apoptosis induction and has demonstrated efficacy in both in vitro cellular assays and in vivo tumor models.
Product Specifications
Field of Research
Cell Biology
Smiles
C[C@H] (NC) C (N[C@H]1CCCC[C@] (CC[C@H]2C (N[C@@H] (C3=CC=CC=C3) C4=CN (CCCCC5=CC=C (CCCCN6N=NC ([C@@H] (NC ([C@@H]7CC[C@@] (CCCC[C@@H]8NC ([C@@H] (NC) C) =O) ([H]) N7C8=O) =O) C9=CC=CC=C9) =C6) C=C5) N=N4) =O) ([H]) N2C1=O) =O.Cl
Molecular Formula
C62H85ClN14O6
Molecular Weight
1157.88
Storage Conditions
-20°C
Notes
For research use only.
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