SMAP-2
SMAP-2 is an orally active small molecule that activates PP2A by binding to its Aα scaffold subunit, inducing a conformational change. It has demonstrated growth-inhibitory effects in KRAS-mutant lung cancer models in both cellular and animal studies, highlighting its potential as a research tool in oncology.
Product Specifications
CAS Number
1809068-70-9
Field of Research
Metabolism Research, Signal Transduction
Smiles
O[C@@H]1[C@H] (CCC[C@H]1N1c2ccccc2CCc2ccccc12) NS (=O) (=O) c1ccc (OC (F) (F) F) cc1
Molecular Formula
C27H27F3N2O4S
Molecular Weight
532.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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