SSTC3
SSTC3 is a potent small molecule activator of casein kinase 1α (CK1α) with a 32 nM Kd, functioning as an inhibitor of WNT signaling and HIF1α. It demonstrates antitumor activity, suppressing SHH medulloblastoma growth in vivo, and is a valuable tool for studying oncogenic pathways in cancer research.
Product Specifications
CAS Number
1242422-09-8
Product Name Alternative
CK1, beta-catenin, betacatenin, bcatenin, Casein Kinase, CaseinKinase, Wnt/β-catenin, Wnt/betacatenin, Wnt/b-catenin, Wnt, SSTC 3, SSTC3, SSTC-3, βcatenin
Field of Research
Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.65% (May vary between batches)
Solubility
DMSO:100 mg/mL (192.85 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.71 mM)
Smiles
CN (c1ccc (cc1) C (F) (F) F) S (=O) (=O) c1ccc (cc1) C (=O) Nc1nc (cs1) -c1ccccn1
Molecular Formula
C23H17F3N4O3S2
Molecular Weight
518.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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