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Tankyrase-IN-2

Tankyrase-IN-2 is a potent, selective, and orally bioavailable small molecule inhibitor, demonstrating high affinity for TNKS1 (IC50=10 nM) and TNKS2 (IC50=7 nM) with significantly weaker activity against PARP1. It is a valuable chemical probe for studying Wnt/β-catenin signaling in cancer research and has been utilized in both cellular and animal models of disease.

Product Specifications

CAS Number

1588870-36-3

Field of Research

Epigenetics & Chromatin, Molecular Biology, Signal Transduction, Stem Cell & Developmental Biology

Smiles

CC (C) (O) c1ccc (cc1) -c1nc2c (F) cc (F) cc2c (=O) [nH]1

Molecular Formula

C17H14F2N2O2

Molecular Weight

316.3

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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