Purified Anti-Human CD194 Antibody[L291H4]
Product Specifications
Background
High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G (i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.
Abbreviation
CD194
Gene ID
1233
UniProt
P51679
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human CD194 protein
Target
CCR; CKR; MGC; HGCN; CMKBR; ChemR; CC-CKR; CC-CKR-4; ChemR13; CKR4; HGCN:14099; K5-5; MGC88293; CMKBR4; CCR4; C-C motif chemokine receptor 4; CD194
Clonality
Monoclonal
Clone
L291H4
Conjugation
Unconjugated
Applications
FCM
Field of Research
Immunology; Cardiovascular
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Isotype
Mouse IgG1, κ
Available Sizes
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