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TP-008

TGFβRI-IN-2 is a potent, selective, and orally bioavailable ALK5 inhibitor with pIC50 and pEC50 values of 7.6 and 6.63, respectively. This compound is a valuable research tool for investigating TGF-β signaling in fibrotic disease models, cancer biology, and other cellular processes both in vitro and in vivo.

Product Specifications

CAS Number

1976038-41-1

Field of Research

Stem Cell & Developmental Biology

Smiles

O=C1N (C=2C (N1CC (N) =O) =CN=CC2) C=3C=C (N=CC3C) C4=C (F) C=CC (Cl) =C4

Molecular Formula

C20H15ClFN5O2

Molecular Weight

411.82

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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