TG 100801
TG-100801 is a dual VEGFR2 and Src/YES kinase inhibitor investigated as a potential therapeutic for age-related macular degeneration (AMD) . It has demonstrated efficacy in preclinical models, reducing choroidal neovascularization in vivo and inhibiting endothelial cell proliferation in vitro.
Product Specifications
CAS Number
867331-82-6
Product Name Alternative
TG 100801, TG 100572, TG100801, TG-100801, Src, PDGFRβ, Yes, VEGFR2, VEGFR1, FGFR1, FGFR2
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.28% (May vary between batches)
Solubility
DMSO:3 mg/mL (5.17 mM) ; H2O:< 0.1 mg/mL (insoluble)
Smiles
Cc1cc (cc2nnc (Nc3ccc (OCCN4CCCC4) cc3) nc12) -c1cc (OC (=O) c2ccccc2) ccc1Cl
Molecular Formula
C33H30ClN5O3
Molecular Weight
580.08
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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