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TG 100801

TG-100801 is a dual VEGFR2 and Src/YES kinase inhibitor investigated as a potential therapeutic for age-related macular degeneration (AMD) . It has demonstrated efficacy in preclinical models, reducing choroidal neovascularization in vivo and inhibiting endothelial cell proliferation in vitro.

Product Specifications

CAS Number

867331-82-6

Product Name Alternative

TG 100801, TG 100572, TG100801, TG-100801, Src, PDGFRβ, Yes, VEGFR2, VEGFR1, FGFR1, FGFR2

Field of Research

Cardiovascular Research, Signal Transduction

Purity

99.28% (May vary between batches)

Solubility

DMSO:3 mg/mL (5.17 mM) ; H2O:< 0.1 mg/mL (insoluble)

Smiles

Cc1cc (cc2nnc (Nc3ccc (OCCN4CCCC4) cc3) nc12) -c1cc (OC (=O) c2ccccc2) ccc1Cl

Molecular Formula

C33H30ClN5O3

Molecular Weight

580.08

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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