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TPA-023B

TPA-023B is a subtype-selective GABAA receptor ligand, functioning as a high-affinity partial agonist at α2/α3 subunits and an antagonist at the α1 subunit. This pharmacological profile underlies its non-sedating anxiolytic-like effects, making it a valuable research tool for studying anxiety neurobiology in both in vitro binding assays and in vivo behavioral models.

Product Specifications

CAS Number

425377-76-0

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Smiles

CC (C) (O) c1cnn2c (cnc2n1) -c1ccc (F) c (c1) -c1c (F) cccc1C#N

Molecular Formula

C21H15F2N5O

Molecular Weight

391.37

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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