TPA-023B
TPA-023B is a subtype-selective GABAA receptor ligand, functioning as a high-affinity partial agonist at α2/α3 subunits and an antagonist at the α1 subunit. This pharmacological profile underlies its non-sedating anxiolytic-like effects, making it a valuable research tool for studying anxiety neurobiology in both in vitro binding assays and in vivo behavioral models.
Product Specifications
CAS Number
425377-76-0
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
CC (C) (O) c1cnn2c (cnc2n1) -c1ccc (F) c (c1) -c1c (F) cccc1C#N
Molecular Formula
C21H15F2N5O
Molecular Weight
391.37
Storage Conditions
-20°C
Notes
For research use only.
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