PF-06733804
PF-06733804 is a potent, pan-Trk inhibitor demonstrating low nanomolar IC50 values against TrkA, TrkB, and TrkC in cellular assays. It exhibits anti-hyperalgesic activity in vivo, making it a valuable research tool for studying neuropathic pain and oncology-related Trk signaling pathways in both in vitro and in vivo models.
Product Specifications
CAS Number
1873373-33-1
Field of Research
Signal Transduction
Smiles
O ([C@H]1CN (C (CC2=CC=C (OC (F) (F) F) C=C2) =O) CC1 (F) F) C=3C=C (C (NC) =O) C=NC3N
Molecular Formula
C20H19F5N4O4
Molecular Weight
474.38
Storage Conditions
-20°C
Notes
For research use only.
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