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TRPA1 Antagonist 1

TRPA1 Antagonist 1 is a potent, selective TRPA1 channel blocker with an IC50 of 8 nM. This compound is administered as a methylene phosphate prodrug, which is metabolized in vivo to release the active parent molecule. It is a valuable research tool for investigating TRPA1-mediated pathways in pain, inflammation, and respiratory models, both in cellular assays and animal studies.

Product Specifications

CAS Number

1984825-08-2

Field of Research

Neuroscience; Pharmacology & Drug Discovery, Pharmacology & Drug Discovery

Smiles

C[C@H]1[C@@H] (C[C@@H] (C (N (Cc2c (F) cnc (c3cnc (C (F) (F) F) nc3) c2) COP ([O-]) ([O-]) =O) =O) N1S (=O) (c4ccc (F) cc4) =O) F.[Na+].[Na+]

Molecular Formula

C24H20F6N5Na2O7PS

Molecular Weight

713.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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