Ropsacitinib
Ropsacitinib (PF-06826647) is a potent and selective TYK2 inhibitor that targets the kinase's JH1 domain with an IC50 of 17 nM. This small molecule is a valuable research tool for investigating TYK2-mediated signaling in immunological and inflammatory diseases, with utility in both cellular and animal models.
Product Specifications
CAS Number
2127109-84-4
Product Name Alternative
Ropsacitinib, PF 06826647, PF-06826647, PF06826647, Tyrosine Kinases, TyrosineKinases, TYK2 JH1, Tyk2-IN-8
Field of Research
Signal Transduction
Purity
99.85% (May vary between batches)
Solubility
DMSO:10 mg/mL (26.08 mM)
Smiles
C (C#N) [C@@]1 (C[C@H] (C#N) C1) N2C=C (C=N2) C=3C=4N (C=C (N3) C=5C=NN (C) C5) N=CC4
Molecular Formula
C20H17N9
Molecular Weight
383.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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