VDR agonist 1
VDR agonist 1 (compound 28) is a potent nonsteroidal Vitamin D receptor agonist (IC50 = 690 nM in MCF-7 cells) . It arrests the cell cycle via p21/p27 upregulation and promotes apoptosis by modulating BAX/Bcl-2, making it a useful research tool for studying VDR signaling in cancer models both in vitro and in vivo.
Product Specifications
CAS Number
2269494-43-9
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery
Smiles
C (CC) (CC) (C=1C=C (C (NCCN (CC) CC) =O) N (CC) C1) C2=CC (C) =C (/C=C/C (CC) (CC) O) C=C2
Molecular Formula
C32H51N3O2
Molecular Weight
509.77
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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