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Seviteronel

Seviteronel (VT-464) is a dual-action investigational agent, functioning as both a CYP17 lyase inhibitor and an androgen receptor antagonist. It is utilized in preclinical and clinical research for hormone-driven cancers, including studies in castration-resistant prostate cancer and androgen receptor-positive breast cancer models.

Product Specifications

CAS Number

1610537-15-9

Product Name Alternative

H-CYP17 Lyase, CYP17, Androgen Receptor, AndrogenReceptor, Seviteronel, VT 464, VT464, VT-464

Field of Research

Metabolism Research

Purity

99.67% (May vary between batches)

Solubility

DMSO:40 mg/mL (100.17 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.01 mM)

Smiles

CC (C) [C@@] (O) (c1c[nH]nn1) c1ccc2cc (OC (F) F) c (OC (F) F) cc2c1

Molecular Formula

C18H17F4N3O3

Molecular Weight

399.34

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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