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VU0364770 hydrochloride

VU0364770 hydrochloride is a selective positive allosteric modulator (PAM) of the metabotropic glutamate receptor 4 (mGlu4), with EC50 values of 290 nM at rat and 1.1 μM at human receptors. This compound is a valuable research tool for investigating mGlu4 function in models of neurological disorders such as Parkinson's disease, both in vitro and in vivo.

Product Specifications

CAS Number

1414842-70-8

Field of Research

Neuroscience

Smiles

Cl.Clc1cccc (NC (=O) c2ccccn2) c1

Molecular Formula

C12H10Cl2N2O

Molecular Weight

269.13

Storage Conditions

-20°C

Notes

For research use only.

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